A section of the eastbound Highway 402 at Watford was closed for several hours after a collision Tuesday evening.
OPP responded to the single-vehicle crash at around 6:15 p.m.
Police say a vehicle left the highway just east of Forest Road, rolled several times and entered the centre median.
The driver was taken to hospital with non-life threatening injuries.
Lambton EMS and volunteer firefighters also responded.
The eastbound lanes of the highway were closed at Forest Road, reopening to traffic just before midnight according to the Ministry of Transportation.
Anyone who may have witnessed the crash is asked contact Lambton OPP at 519-882-1011 or Crime Stoppers at 1-800-222-8477 (TIPS).