Fire officials can't say what started a house fire on Chatham Street East in Windsor.
Firefighters arrived at the home near Louis Avenue around 9 p.m. and fought the flames into the early morning hours.
No one was hurt, and the cause is listed as undetermined, but the damage is calculated at $500,000.
The fire was the second in as many days in the neighbourhood.
On Tuesday night, a home on Louis Avenue between Aylmer Avenue and University Avenue East went up in flames.
Windsor Police are investigating that fire.