South Bruce OPP have closed Hwy 21 in Kincardine on Tuesday afternoon due to a multi-vehicle collision.
As of 10 p.m., the road remains closed between Hwy 9 and North Line.
According to a spokesperson for the OPP, the collision involved four vehicles and three people were taken to hospital.
According to witnesses, Ornge helicopters responded.
The collision is under investigation.
A spokesperson for Bluewater District School Board said the second wave of buses for Kincardine Township-Tiverton Public School were impacted by road the closure, and arrangements were made with families for student pickups.
More information to come.
