The U-S National Academy of Sciences says it can find no substantiated evidence that foods from genetically-engineered crops are less safe for human consumption than non-GE crops.
The Academy's Committee on Genetically Engineered Crops looked at the evidence related to claims of positive and negative effects of existing genetically engineered crops.
It was unable to find any evidence of linkage between GE crops and the incidence of cancers and other human-health problems.
The committee also concluded that GE soybean, corn and cotton have generally had favourable economic outcomes for producers.
The committee says evidence suggests crops with the insect resistant trait generally decreased yield losses.
It also says widespread planting of those crops decreased the abundance of specific pests in the landscape, helping reducing damage to crops that did not have that trait.
The committee did have concerns about glyphosate-resistant weeds, and suggested sustainable use of genetically-engineered crops requires the use of integrated pest-management strategies.